{"id":1312,"date":"2025-11-24T15:10:48","date_gmt":"2025-11-24T11:40:48","guid":{"rendered":"https:\/\/petroalton.ir\/en\/?post_type=product&#038;p=1312"},"modified":"2025-11-25T21:27:47","modified_gmt":"2025-11-25T17:57:47","slug":"isothiazolinone","status":"publish","type":"product","link":"https:\/\/petroalton.ir\/en\/product\/isothiazolinone\/","title":{"rendered":"Isothiazolinone"},"content":{"rendered":"<p><strong>What is Isothiazolinone?<\/strong><\/p>\n<p><strong>Isothiazolinone (or Isothiazolinone compound)<\/strong> is a biocidal chemical that appears as a clear, colorless to light yellow liquid. It is a mixture of <strong>Methyl Isothiazolinone (MI)<\/strong> and <strong>Chloro Methyl Isothiazolinone (MCI)<\/strong> in a 3:1 ratio.<br \/>\nThis compound disrupts the bonds within bacteria and algae, preventing them from feeding and leading to their destruction. Therefore, it acts as an <strong>antimicrobial<\/strong>, effective against both <strong>Gram-positive and Gram-negative bacteria<\/strong>, as well as <strong>yeasts and fungi<\/strong>.<br \/>\nIt is widely used in detergents such as shampoos to prevent bacterial contamination\u2014particularly in humid environments like bathrooms.<\/p>\n<p>Isothiazolinone is <strong>completely water-soluble<\/strong> and is mainly used in <strong>cosmetic and personal care industries<\/strong>. Tests show that it has <strong>no side effects<\/strong> and <strong>no impact on the human nervous system<\/strong>.<\/p>\n<p><strong>Molecular Structure of Isothiazolinone<\/strong><\/p>\n<p><em>(Structure illustration section)<\/em><\/p>\n<p><strong>Isothiazolinone Derivatives<\/strong><\/p>\n<p>This compound itself has limited application, but its <strong>derivatives<\/strong> are widely used as <strong>biocides<\/strong>. Major derivatives include:<\/p>\n<ul>\n<li><strong>Methylchloroisothiazolinone (MCI \/ MCIT)<\/strong><\/li>\n<li><strong>Methylisothiazolinone (MI \/ MIT)<\/strong><\/li>\n<li><strong>Benzisothiazolinone (BIT)<\/strong><\/li>\n<li><strong>Octylisothiazolinone (OIT)<\/strong><\/li>\n<li><strong>Butylbenzisothiazolinone (BBIT)<\/strong><\/li>\n<\/ul>\n<p><strong>Types of Isothiazolinone<\/strong><\/p>\n<ul>\n<li><strong>Isothiazolinone 14%:<\/strong><br \/>\nContains a higher concentration of active ingredient, making it more expensive.<\/li>\n<li><strong>Isothiazolinone 1.5%:<\/strong><br \/>\nDiluted form of the 14% solution. This version is the most widely used.<\/li>\n<\/ul>\n<p><strong>Applications of Isothiazolinone in Industries<\/strong><\/p>\n<p>Used for <strong>improving preservation<\/strong>, <strong>controlling bacterial and fungal growth<\/strong>, and <strong>disinfection<\/strong> in various sectors such as metalworking and chemical storage.<\/p>\n<ol>\n<li><strong> Use in Detergents<\/strong><\/li>\n<\/ol>\n<p>Applied in the production of <strong>detergents and cleaning products<\/strong> (dishwashing liquids, hand soaps, shampoos, and household cleaners).<\/p>\n<ol start=\"2\">\n<li><strong> Use in Water and Wastewater Treatment<\/strong><\/li>\n<\/ol>\n<p>As a strong antimicrobial agent, it disrupts bacterial and algal growth in <strong>cooling towers, water storage systems, and wastewater treatment facilities<\/strong> (via MIT and CMIT derivatives).<\/p>\n<ol start=\"3\">\n<li><strong> Use as a Preservative<\/strong><\/li>\n<\/ol>\n<p>Added to <strong>cosmetic and personal care products<\/strong> (like sunscreens, lotions, and moisturizers) to prevent spoilage.<\/p>\n<ol start=\"4\">\n<li><strong> Use in Oil, Gas, and Petrochemical Industries<\/strong><\/li>\n<\/ol>\n<p>Used for microbial control in <strong>oil fields, pipelines, and drilling fluids<\/strong>.<\/p>\n<ol start=\"5\">\n<li><strong> Use in Pharmaceuticals<\/strong><\/li>\n<\/ol>\n<p>Applied as a <strong>protease inhibitor<\/strong> in medications for treating <strong>anxiety and depression<\/strong>.<\/p>\n<p><strong>Other Applications<\/strong><\/p>\n<ul>\n<li>Increasing the shelf life of wood products<\/li>\n<li>Paper and leather industries<\/li>\n<li>Replacement for formalin in detergents<\/li>\n<li>Fuel storage tanks<\/li>\n<li>Fertilizer, pesticide, and agrochemical production<\/li>\n<li>Metalworking fluids<\/li>\n<li>Oil extraction systems<\/li>\n<li>Disinfection of medical devices<\/li>\n<li>Used in butadiene rubber and latex compounds<\/li>\n<li>Air conditioning systems<\/li>\n<li>Polyvinyl alcohol and acrylic emulsions<\/li>\n<li>Water-based paints and coatings<\/li>\n<li>Construction materials (adhesives, paints, resins)<\/li>\n<li>Printer inks<\/li>\n<\/ul>\n<p><strong>Advantages of Isothiazolinone<\/strong><\/p>\n<ul>\n<li>Non-toxic and high quality<\/li>\n<li>Water-based formulation<\/li>\n<li>Non-foaming and biodegradable<\/li>\n<li>Compatible with non-ionic surfactants<\/li>\n<li>Excellent antimicrobial, bactericidal, and fungicidal properties<\/li>\n<li>Effective disinfectant for water systems<\/li>\n<li>Non-oxidizing<\/li>\n<li>Stable over a wide pH range<\/li>\n<li>Highly soluble and disperses rapidly in cold water<\/li>\n<\/ul>\n<p><strong>Factors Affecting Stability<\/strong><\/p>\n<p>Isothiazolinone remains effective across a wide <strong>pH<\/strong> and <strong>temperature range<\/strong>, but <strong>high temperature and alkalinity<\/strong> reduce its stability, while it remains more stable under <strong>acidic conditions<\/strong>.<\/p>\n<p><strong>Production Method<\/strong><\/p>\n<p>Industrial synthesis involves <strong>ring closure reactions<\/strong> of <strong>3-mercaptopropanamide derivatives<\/strong> or via <strong>acrylic acid<\/strong>.<br \/>\nThe process converts <strong>thiol amide groups<\/strong> into reactive intermediates through <strong>chlorination or oxidation<\/strong>, forming the <strong>isothiazolinone ring<\/strong>.<br \/>\nAnother method includes <strong>adding thiocyanate to propargyl amides<\/strong>.<\/p>\n<p><strong>Factors Affecting Price<\/strong><\/p>\n<p>The <strong>price<\/strong> of Isothiazolinone depends on:<\/p>\n<ul>\n<li>Product volume<\/li>\n<li>Purity percentage<\/li>\n<li>Exchange rates<\/li>\n<li>Manufacturer brand<\/li>\n<\/ul>\n<p>For up-to-date pricing, contact <strong>Petro Alton experts<\/strong>.<\/p>\n<p><strong>What is Methyl Isothiazolinone (MIT)?<\/strong><\/p>\n<p><strong>2-Methyl-4-isothiazolin-3-one<\/strong><br \/>\nAdding a <strong>methyl substituent<\/strong> to the isothiazolinone ring produces <strong>MIT<\/strong>, a 5-membered heterocyclic compound containing <strong>nitrogen, sulfur, and carbonyl<\/strong>.<\/p>\n<p><strong>What is Methylchloroisothiazolinone (MCIT)?<\/strong><\/p>\n<p><strong>5-Chloro-2-methyl-4-isothiazolin-3-one<\/strong><br \/>\nBy adding <strong>methyl and chlorine substituents<\/strong>, the compound <strong>MCIT (commercial name: Kathon CG)<\/strong> is formed.<br \/>\nFirst used in <strong>cosmetics in the 1970s<\/strong>.<\/p>\n<p><strong>Benzisothiazolinone (BIT)<\/strong><\/p>\n<p><em>(Structural formula illustration section)<\/em><\/p>\n<p><strong>Safety Precautions<\/strong><\/p>\n<p>Since <strong>Isothiazolinone<\/strong> can cause <strong>allergic reactions<\/strong>, its concentration in cosmetics must be within regulated limits.<br \/>\nPeople with sensitive skin should check product labels and perform a <strong>patch test<\/strong> before use. If no irritation occurs after 24 hours, the product is safe for use.<\/p>\n<p><strong>Packaging and Storage<\/strong><\/p>\n<ul>\n<li>Store away from direct sunlight, in a <strong>dry, well-ventilated area<\/strong>.<\/li>\n<li>Available in <strong>20 kg and 60 kg containers<\/strong>, and <strong>200 kg drums<\/strong>.<\/li>\n<\/ul>\n<p><strong>Market and Sales<\/strong><\/p>\n<p>Proper sourcing of raw materials is critical to ensure product quality.<br \/>\n<strong>Petro Alton Tajhiz Company<\/strong>, as a major supplier of industrial chemicals, offers bulk <strong>Isothiazolinone (1.5% and 14%)<\/strong> in various grades \u2014 <strong>pharmaceutical, cosmetic, and industrial<\/strong>.<br \/>\nFor <strong>price inquiries and purchase<\/strong>, contact us via the numbers listed on our website.<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p><strong>Technical Specifications of Isothiazolinone<\/strong><\/p>\n<p><strong>Appearance:<\/strong> Clear, colorless to light yellow transparent liquid<br \/>\n<strong>Molecular Weight:<\/strong> 101.127 g\/mol<br \/>\n<strong>pH:<\/strong> 4 \u2013 5<br \/>\n<strong>Density (at 25\u00b0C):<\/strong> 0.990 \u2013 1.100 g\/cm\u00b3<br \/>\n<strong>Boiling Point:<\/strong> 86.33\u00b0C<br \/>\n<strong>Solubility:<\/strong> Completely soluble in water<br \/>\n<strong>Methyl Isothiazolinone Content:<\/strong> 0.2 \u2013 0.4%<br \/>\n<strong>Methylchloroisothiazolinone Content:<\/strong> 1 \u2013 1.2%<\/p>\n<p><strong>Isothiazolinone Purchase<\/strong><\/p>\n<p><strong>Petro Alton Tajhiz Company<\/strong>, as one of the leading suppliers of chemical materials across Iran, provides <strong>Isothiazolinone<\/strong> with the highest quality and shortest delivery time.<br \/>\nFor purchasing and free consultation, please contact our experts: <strong>021-59236<\/strong><\/p>\n","protected":false},"featured_media":1314,"comment_status":"open","ping_status":"closed","template":"redux-templates_full_width","meta":[],"product_brand":[],"product_cat":[15],"product_tag":[],"class_list":["post-1312","product","type-product","status-publish","has-post-thumbnail","product_cat-15","first","instock","shipping-taxable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/petroalton.ir\/en\/wp-json\/wp\/v2\/product\/1312","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/petroalton.ir\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/petroalton.ir\/en\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/petroalton.ir\/en\/wp-json\/wp\/v2\/comments?post=1312"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/petroalton.ir\/en\/wp-json\/wp\/v2\/media\/1314"}],"wp:attachment":[{"href":"https:\/\/petroalton.ir\/en\/wp-json\/wp\/v2\/media?parent=1312"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/petroalton.ir\/en\/wp-json\/wp\/v2\/product_brand?post=1312"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/petroalton.ir\/en\/wp-json\/wp\/v2\/product_cat?post=1312"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/petroalton.ir\/en\/wp-json\/wp\/v2\/product_tag?post=1312"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}